Gene of the issue: RUNX1 mutations and inherited bleeding

Platelets. 2017 Mar;28(2):208-210. doi: 10.1080/09537104.2017.1280151. Epub 2017 Feb 17.

Authors

Neil V Morgan¹, Martina E Daly²

Affiliations

¹ a Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham , Birmingham , UK.
² b Department of Infection , Immunity and Cardiovascular Disease, University of Sheffield , Sheffield , UK.

No abstract available

Keywords: Bleeding; RUNX1 gene; inherited mutations; platelets.

MeSH terms

Blood Coagulation Disorders, Inherited / genetics*
Blood Coagulation Disorders, Inherited / pathology
Blood Platelet Disorders / genetics*
Blood Platelet Disorders / pathology
Blood Platelets / metabolism*
Blood Platelets / pathology
Chromosomes, Human, Pair 21 / chemistry
Core Binding Factor Alpha 2 Subunit / genetics*
Gene Expression
Genes, Dominant
Hemorrhage / congenital
Hemorrhage / genetics*
Hemorrhage / physiopathology
Humans
Leukemia, Myeloid, Acute / genetics*
Leukemia, Myeloid, Acute / pathology
Mutation*
Platelet Count
Protein Domains
RNA, Messenger / genetics*

Substances

Core Binding Factor Alpha 2 Subunit
RNA, Messenger
RUNX1 protein, human

Supplementary concepts

Platelet Disorder, Familial, with Associated Myeloid Malignancy

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