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. 2017 Mar 9;15(3):e2002050.
doi: 10.1371/journal.pbio.2002050. eCollection 2017 Mar.

All Biology Is Computational Biology

Free PMC article

All Biology Is Computational Biology

Florian Markowetz. PLoS Biol. .
Free PMC article


Here, I argue that computational thinking and techniques are so central to the quest of understanding life that today all biology is computational biology. Computational biology brings order into our understanding of life, it makes biological concepts rigorous and testable, and it provides a reference map that holds together individual insights. The next modern synthesis in biology will be driven by mathematical, statistical, and computational methods being absorbed into mainstream biological training, turning biology into a quantitative science.

Conflict of interest statement

The authors have declared that no competing interests exist.


Fig 1
Fig 1. Carl von Linné, the Swedish botanist and father of taxonomy, would be a computational biologist today.
Image credit: Nationalmuseum Stockholm.

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