Cardio-oncology Related to Heart Failure: Common Risk Factors Between Cancer and Cardiovascular Disease

Anne Blaes; Anna Prizment; Ryan J Koene; Suma Konety

doi:10.1016/j.hfc.2016.12.006

Cardio-oncology Related to Heart Failure: Common Risk Factors Between Cancer and Cardiovascular Disease

Heart Fail Clin. 2017 Apr;13(2):367-380. doi: 10.1016/j.hfc.2016.12.006.

Authors

Anne Blaes¹, Anna Prizment², Ryan J Koene³, Suma Konety⁴

Affiliations

¹ Division of Hematology and Oncology, University of Minnesota, 420 Delaware Street, Southeast, MMC 480, Minneapolis, MN 55455, USA. Electronic address: Blaes004@umn.eu.
² School of Public Health, University of Minnesota, 1300 South 2nd Street, 7525A, Minneapolis, MN 55454, USA.
³ Division of Cardiology, University of Minnesota, 420 Delaware Street, Southeast, MMC 480, Minneapolis, MN 55455, USA.
⁴ Division of Cardiology, University of Minnesota, 420 Delaware Street, Southeast, MMC 508, Minneapolis, MN 55455, USA.

Abstract

There is a growing body of evidence that suggests cancer and cardiovascular disease have a shared biological mechanism. Although there are several shared risk factors for both diseases, including advancing age, gender, obesity, diabetes, physical activity, tobacco use, and diet, inflammation and biomarkers, such as insulinlike growth factor 1, leptin, estrogen, and adiponectin, may also play a role in the biology of these diseases. This article provides an overview of the shared biological mechanism between cancer and cardiovascular disease.

Keywords: Cancer; Cardiooncology; Heart disease; Risk; Risk factors.

Publication types

Review

MeSH terms

Age Factors
Biomarkers / metabolism
Cardiovascular Diseases / etiology*
Cardiovascular Diseases / metabolism
Female
Humans
Male
Neoplasms / etiology*
Neoplasms / metabolism
Risk Factors
Sex Factors

Substances

Biomarkers

Abstract

Publication types

MeSH terms

Substances

Grants and funding