Pediatric Heart Failure: A Practical Guide to Diagnosis and Management

Pediatr Neonatol. 2017 Aug;58(4):303-312. doi: 10.1016/j.pedneo.2017.01.001. Epub 2017 Feb 1.

Abstract

Pediatric heart failure represents an important cause of morbidity and mortality in childhood. Currently, there are well-established guidelines for the management of heart failure in the adult population, but an equivalent consensus in children is lacking. In the clinical setting, ensuring an accurate diagnosis and defining etiology is essential to optimal treatment. Diuretics and angiotensin-converting enzyme inhibition are the first-line therapies, whereas beta-blockers and devices for electric therapy are less used in children than in adults. In the end-stage disease, heart transplantation is the best choice of treatment, while a left ventricular assist device can be used as a bridge to transplantation (due to the difficulties in finding organ donors), recovery (in the case of myocarditis), or destination therapy (for patients with systemic disease).

Keywords: cardiomyopathies; congenital heart diseases; pediatric cardiac transplantation; pediatric heart failure.

Publication types

  • Review

MeSH terms

  • Adult
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Child
  • Diuretics / therapeutic use
  • Heart Failure / diagnosis*
  • Heart Failure / etiology
  • Heart Failure / therapy*
  • Heart Transplantation
  • Heart-Assist Devices
  • Humans
  • Tissue Donors

Substances

  • Angiotensin-Converting Enzyme Inhibitors
  • Diuretics