Hepatoprotective Effects of Nicotiflorin from Nymphaea candida against Concanavalin A-Induced and D-Galactosamine-Induced Liver Injury in Mice

Int J Mol Sci. 2017 Mar 8;18(3):587. doi: 10.3390/ijms18030587.

Abstract

Nymphaea candida was used to treat hepatitis in Ugyhur medicine, and nicotiflorin (kaempferol 3-O-β-rutinoside) is the main characteristic component in this plant [...].

Keywords: Concanavalin A; D-galactosamine; Nymphaea candida; hepatoprotective; nicotiflorin.

MeSH terms

  • Animals
  • Chemical and Drug Induced Liver Injury / drug therapy
  • Chemical and Drug Induced Liver Injury / metabolism*
  • Chemical and Drug Induced Liver Injury / pathology*
  • Concanavalin A / adverse effects*
  • Cytokines / metabolism
  • Disease Models, Animal
  • Flavonoids / chemistry
  • Flavonoids / pharmacology*
  • Galactosamine / adverse effects*
  • Liver Function Tests
  • Mice
  • Molecular Structure
  • Nymphaea / chemistry*
  • Oxidation-Reduction / drug effects
  • Oxidative Stress
  • Phenols / chemistry
  • Phenols / pharmacology*
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Protective Agents / chemistry
  • Protective Agents / pharmacology*

Substances

  • Cytokines
  • Flavonoids
  • Phenols
  • Plant Extracts
  • Protective Agents
  • nicotiflorin
  • Concanavalin A
  • Galactosamine