Management of soft-tissue sarcomas; treatment strategies, staging, and outcomes

Eyal M Ramu; Matthew T Houdek; Christian E Isaac; Colleen I Dickie; Peter C Ferguson; Jay S Wunder

doi:10.1051/sicotj/2017010

Management of soft-tissue sarcomas; treatment strategies, staging, and outcomes

SICOT J. 2017:3:20. doi: 10.1051/sicotj/2017010. Epub 2017 Mar 10.

Authors

Eyal M Ramu¹, Matthew T Houdek¹, Christian E Isaac¹, Colleen I Dickie², Peter C Ferguson¹, Jay S Wunder¹

Affiliations

¹ University of Toronto Musculoskeletal Oncology Unit, Mount Sinai Hospital, Toronto, M5G 1X5 Ontario, Canada - Department of Surgical Oncology, Princess Margaret Cancer Center, University of Toronto, Toronto, M5G 2C4 Ontario, Canada - Division of Orthopedic Surgery, Department of Surgery, University of Toronto, Toronto, M5G 2C4 Ontario, Canada.
² Department of Radiation Oncology, Princess Margaret Cancer Center, University of Toronto, Toronto, M5G 2C4 Ontario, Canada.

Abstract

Soft-tissue sarcomas (STS) are a rare group of malignant tumors which can affect any age group. For the majority of patients who present with a localized STS, treatment involves a multidisciplinary team decision-making approach ultimately relying on surgical resection with or without adjuvant radiation for successful limb salvage. The goals of treatment are to provide the patient with a functional extremity without local tumor relapse. The purpose of this article is to review the treatment of extremity STS, with a focus on staging, treatment options, and outcomes.