Fetal Magnetic Resonance Imaging Findings in Prenatal Zika Virus Infection

Fetal Diagn Ther. 2017;42(2):153-157. doi: 10.1159/000454860. Epub 2017 Mar 14.


Brain lesions and malformations have been described on ultrasonography of prenatal Zika infection; however, there are scarce reports about fetal magnetic resonance (MR) findings. We report 3 cases of fetuses with confirmed intrauterine Zika virus infection evaluated by ultrasound and fetal MR. Various morphometric measurements were assessed and brain maturation was calculated with the fetal total maturation score. Fetuses with prenatal Zika virus infection showed retardation in brain maturation indexes evaluated by fetal MR. Brain calcifications were demonstrated by neurosonography in all cases, while fetal MR characterized the specific type of cortical development malformation.

Keywords: Congenital Zika virus syndrome; Fetal magnetic resonance; Fetal ultrasound; Intrauterine infection.

Publication types

  • Case Reports

MeSH terms

  • Brain / diagnostic imaging*
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnostic imaging*
  • Zika Virus / isolation & purification
  • Zika Virus Infection / diagnostic imaging*