Clear Cell Renal Cell Carcinoma with Intratumoral Granulomatous Reaction: A Case Report and Review of the Literature

J Pathol Transl Med. 2017 May;51(3):325-328. doi: 10.4132/jptm.2016.09.08. Epub 2017 Mar 14.

Abstract

Granulomatous reaction associated with clear cell renal cell carcinoma (CCRCC) is a rare finding, and only a few cases have been described in the literature. It is postulated to occur due to cancer-related antigenic factors such as cancer cells themselves or soluble tumor antigens shed into the blood. Herein, we describe a case of a 56-year-old male patient diagnosed with CCRCC with intratumoral granulomatous inflammation.

Keywords: Carcinoma, renal cell; Granulomatous reaction; Kidney neoplasms.