Antimicrobial Metabolites from Streptomyces sp. SN0280
- PMID: 28294616
- DOI: 10.1021/acs.jnatprod.6b01016
Antimicrobial Metabolites from Streptomyces sp. SN0280
Abstract
One new indole derivative, chloroindole (1), one new diketone, streptoone A (2), two new ketonic acids, streptoones B (3) and C (4), and one known macrolide antibiotic, X-14952B (5), were isolated from Streptomyces sp. SN0280. Extensive NMR, HRESIMS, and IR analysis was used to elucidate their structures. Streptoone A (2) displayed antibacterial activity (MIC value of 7.81 μg/mL) against Clavibater michiganensis, comparable with the positive control streptomycin (MIC value of 7.81 μg/mL). Streptoone B (3) showed antifungal activity (MIC value of 15.63 μg/mL) against Phytophthora capsici (positive control carbendazol MIC value of 7.81 μg/mL). These molecules provide new templates for the potential treatment and management of these phytopathogens.
Similar articles
-
Purification and structure elucidation of antifungal and antibacterial activities of newly isolated Streptomyces sp. strain US80.Res Microbiol. 2005 Apr;156(3):341-7. doi: 10.1016/j.resmic.2004.10.006. Epub 2004 Dec 15. Res Microbiol. 2005. PMID: 15808937
-
Oridamycins A and B, anti-Saprolegnia parasitica indolosesquiterpenes isolated from Streptomyces sp. KS84.J Nat Prod. 2010 Apr 23;73(4):698-701. doi: 10.1021/np1000522. J Nat Prod. 2010. PMID: 20369841
-
A new prenylated indole derivative from endophytic actinobacteria Streptomyces sp. neau-D50.Nat Prod Res. 2014;28(7):431-7. doi: 10.1080/14786419.2013.871546. Epub 2014 Jan 21. Nat Prod Res. 2014. PMID: 24443904
-
Antimicrobial metabolites from a marine-derived Actinomycete Streptomyces sp. G278.Nat Prod Res. 2019 Nov;33(22):3223-3230. doi: 10.1080/14786419.2018.1468331. Epub 2018 May 4. Nat Prod Res. 2019. PMID: 29726708
-
Indole diterpenoids from the endophytic fungus Drechmeria sp. as natural antimicrobial agents.Phytochemistry. 2018 Apr;148:21-28. doi: 10.1016/j.phytochem.2018.01.010. Epub 2018 Jan 20. Phytochemistry. 2018. PMID: 29366852
Cited by
-
Talaroterpenoids A-F: Six New Seco-Terpenoids from the Marine-Derived Fungus Talaromyces aurantiacus.Mar Drugs. 2024 Oct 18;22(10):475. doi: 10.3390/md22100475. Mar Drugs. 2024. PMID: 39452883 Free PMC article.
-
iChip-Inspired Isolation, Bioactivities and Dereplication of Actinomycetota from Portuguese Beach Sediments.Microorganisms. 2022 Jul 20;10(7):1471. doi: 10.3390/microorganisms10071471. Microorganisms. 2022. PMID: 35889190 Free PMC article.
-
Isolation and Characterization of Antimicrobial Metabolites from the Sophora tonkinensis-Associated Fungus Penicillium sp. GDGJ-N37.Molecules. 2024 Jan 10;29(2):348. doi: 10.3390/molecules29020348. Molecules. 2024. PMID: 38257261 Free PMC article.
-
Inhibitory potentials of Streptomyces exfoliatus strain 'MUJA10' against bacterial pathogens isolated from rural areas in Riyadh, Saudi Arabia.PLoS One. 2022 Apr 14;17(4):e0266297. doi: 10.1371/journal.pone.0266297. eCollection 2022. PLoS One. 2022. Retraction in: PLoS One. 2024 Jan 25;19(1):e0298008. doi: 10.1371/journal.pone.0298008. PMID: 35421124 Free PMC article. Retracted.
-
Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation.Front Microbiol. 2017 Jul 11;8:1284. doi: 10.3389/fmicb.2017.01284. eCollection 2017. Front Microbiol. 2017. PMID: 28744271 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
