Efficacy of Activated 3X Platelet-Rich Plasma in the Treatment of Androgenic Alopecia

J Stem Cells. 2016;11(4):191-199.

Abstract

Background: Platelet-rich plasma (PRP) has shown remarkable beneficial effects without any major adverse reactions in the treatment of androgenic alopecia .The growth factors in activated autologous PRP induces the proliferation of dermal papilla cells.

Objectives: To investigate the clinical efficacy of Platelet Rich Plasma prepared using Merisis One Step Gel Separation Technology in treatment of androgenic alopecia.

Methods: Five patients were given autologous PRP injections on the affected area of alopecia over a period of three months at interval of two - three weeks and results were assessed.

Results: Three months after the treatment, the patients presented clinical improvement in the hair counts, hair thickness, hair root strength and overall alopecia.

Conclusion: PRP appears to be a cheap, effective and promising therapy for androgenic alopecia with no major adverse effects.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Alopecia / therapy*
  • Blood Platelets / cytology
  • Cytokines / analysis
  • Erythrocytes / cytology
  • Humans
  • Intercellular Signaling Peptides and Proteins / analysis
  • Male
  • Middle Aged
  • Platelet-Rich Plasma / metabolism*
  • Treatment Outcome

Substances

  • Cytokines
  • Intercellular Signaling Peptides and Proteins