Reactivation of Retinopathy of Prematurity Three Years After Treatment With Bevacizumab

Ophthalmic Surg Lasers Imaging Retina. 2017 Mar 1;48(3):255-259. doi: 10.3928/23258160-20170301-10.

Abstract

Although intravitreal injection of anti-vascular endothelial growth factor agents (IVA) can induce rapid regression of retinopathy of prematurity (ROP), late reactivation of the ROP can occur in the form of tractional retinal detachment (TRD) from contracted recurrent extraretinal fibrovascular proliferation. The authors report a case of bilateral TRD for recurrent ROP in a 3-year-old, which is the latest-reported reactivation to date. The authors propose that persistent avascular retina in eyes that have undergone IVA for ROP receive laser ablation to prevent late recurrences. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:255-259.].

Publication types

  • Case Reports

MeSH terms

  • Angiogenesis Inhibitors / administration & dosage
  • Bevacizumab / administration & dosage*
  • Female
  • Fluorescein Angiography
  • Follow-Up Studies
  • Fundus Oculi
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Intravitreal Injections
  • Recurrence
  • Retinopathy of Prematurity / diagnosis
  • Retinopathy of Prematurity / drug therapy*
  • Time Factors

Substances

  • Angiogenesis Inhibitors
  • Bevacizumab