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. 2017 Mar;34(2):211-213.
doi: 10.1111/pde.13089.

Immunohistochemical Staining of Pediatric Solitary Angiokeratomas

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Immunohistochemical Staining of Pediatric Solitary Angiokeratomas

Brea Prindaville et al. Pediatr Dermatol. .

Abstract

The precise etiology and subtype of vessels constituting angiokeratomas is poorly understood. We sought to characterize the vessels by studying prospero-related homeobox gene-1 and D2-40 expression in 22 pediatric solitary angiokeratomas. Routine histologic examination demonstrated a mix of lymph-containing vessels and erythrocyte-filled small vessels. Our results suggest that angiokeratomas may in part be comprised of vessels with lymphatic differentiation.

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