Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases in China and manifests as simple fatty liver, non-alcoholic steatohepatitis, liver cirrhosis, and hepatocellular carcinoma. Studies have shown that intestinal flora can affect the development and progression of NAFLD via the "gut-liver axis" . Probiotics are active microorganisms with beneficial effects on the host, and more and more studies have found that probiotics play a positive role in improving NAFLD. They are cheaper, less harmful, and safer compared with antibiotics and surgery, and therefore, it may become a new method for the prevention and treatment of NAFLD. This article reviews the research advances in probiotics in the treatment of NAFLD, in order to provide a basis for the treatment of NAFLD using probiotics.
非酒精性脂肪性肝病（NAFLD）是我国最常见的慢性肝病之一，临床表现形式包括单纯性脂肪肝、非酒精性脂肪性肝炎及其相关肝硬化和肝细胞癌，研究发现肠道菌群可以通过"肠-肝轴"影响NAFLD的发生发展。益生菌是一类对宿主有益的活性微生物，越来越多的研究发现益生菌在改善NAFLD方面有积极作用，与抗生素和手术相比更加廉价、无害和安全，有望成为防治NAFLD的新方法。现对益生菌治疗NAFLD中的研究进展加以综述，以期为更好地利用益生菌治疗NAFLD提供依据。.
Keywords: Intestinal flora; Nonalcoholic fatty liver disease; Probiotics.