Aging and Autism Spectrum Disorder: A Naturalistic, Longitudinal Study of the Comorbidities and Behavioral and Neuropsychiatric Symptoms in Adults with ASD

J Autism Dev Disord. 2017 Jun;47(6):1708-1715. doi: 10.1007/s10803-017-3095-3.

Abstract

Little is known about Autism Spectrum Disorder (ASD) in persons over age 50. In a retrospective, naturalistic review of 74 individuals aged 30 and older meeting DSM-5 criteria for ASD, the point prevalence of behavioral and neuropsychiatric symptoms (BNPS) declined significantly for 12 of 13 BNPS over a mean of 25 years while many other features of ASD remained stable. GI disorders (68.9%) and seizure disorders (23%) were common, and 25.7% of the sample had a BMI >30. Females were more likely to engage in screaming (p < 0.05) and oppositional behavior (p < 0.05). Current age did not have a significant effect on BNPS prevalence.

Keywords: Adulthood; Aging; Autism spectrum disorder; Neuropsychiatric symptoms.

Publication types

  • Pragmatic Clinical Trial

MeSH terms

  • Adult
  • Aging / psychology*
  • Autism Spectrum Disorder / diagnosis*
  • Autism Spectrum Disorder / epidemiology
  • Autism Spectrum Disorder / psychology*
  • Comorbidity
  • Epilepsy / diagnosis
  • Epilepsy / epidemiology
  • Epilepsy / psychology
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • Social Behavior Disorders / diagnosis*
  • Social Behavior Disorders / epidemiology
  • Social Behavior Disorders / psychology*