Staging of Sinonasal and Ventral Skull Base Malignancies

Otolaryngol Clin North Am. 2017 Apr;50(2):257-271. doi: 10.1016/j.otc.2016.12.004.


Tremendous pathologic diversity among sinonasal and ventral skull base malignancies complicates development of a uniform and prognostically relevant staging system. Because of the comparatively low incidence of these tumors, comprehensive evaluation and comparison of specific staging systems is difficult. The current American Joint Committee on Cancer TNM staging system for sinonasal malignancies is the most common and widely used system in current clinical practice. Alternative systems have been proposed for use with individual histopathologic subtypes. Many of these staging systems are of great utility and accurately predict patient survival. Further research and adjustment of these current staging systems remains an important area of research.

Keywords: Cancer staging; Head and neck cancer; Paranasal sinus malignancy; Skull base.

Publication types

  • Review

MeSH terms

  • Humans
  • Neoplasm Staging
  • Paranasal Sinus Neoplasms / pathology*
  • Paranasal Sinuses / pathology*
  • Prognosis
  • Skull Base / pathology*
  • Skull Base Neoplasms / pathology*
  • Tomography, X-Ray Computed