The Role of Diet and Supplements in Vitiligo Management

Dermatol Clin. 2017 Apr;35(2):235-243. doi: 10.1016/j.det.2016.11.012.


Vitiligo is an autoimmune disorder that involves the interplay between oxidative stress and the immune system. Preliminary observations suggest that the presence of gluten in the diet may play a role in vitiligo development in some patients, but to date vitiligo-specific diets have not been studied. The role of oral supplements, including vitamins, minerals, and botanicals, is increasingly being investigated as adjuncts to conventional medical treatment due to their antioxidant and immunomodulatory activity. Studies suggest that many of these agents may have some efficacy as monotherapy, but more often as adjuncts to topical agents and phototherapy.

Keywords: Autoimmune disease; EGCG; Ginkgo biloba; Oxidative stress; Polypodium leucotomos; Vitamin D; Vitamins; Vitiligo.

Publication types

  • Review

MeSH terms

  • Combined Modality Therapy
  • Diet Therapy*
  • Diet, Gluten-Free
  • Dietary Supplements*
  • Humans
  • Phototherapy*
  • Plant Preparations / therapeutic use*
  • Vitamins / therapeutic use*
  • Vitiligo / therapy*


  • Plant Preparations
  • Vitamins