Microbiology of Acute and Chronic Osteomyelitis and Antibiotic Treatment

Dent Clin North Am. 2017 Apr;61(2):271-282. doi: 10.1016/j.cden.2016.12.001.

Abstract

Osteomyelitis is an inflammation of bone marrow with a tendency for progression, involving the cortical plates and often periosteal tissues, with most cases occurring after trauma to bone or bone surgery or secondary to vascular insufficiency. Antimicrobial therapy and surgical débridement are the primary modalities of osteomyelitis treatment, although often it is associated with a prolonged course, requiring a large commitment between patient and clinician as well as sizable health care costs. Despite surgical and chemotherapeutic advancements, osteomyelitis remains difficult to treat, and no universally accepted protocol for treatment exists.

Keywords: Antibiotic; Jaw; Mandible; Microbiology; Osteomyelitis.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / drug therapy*
  • Chronic Disease
  • Humans
  • Osteomyelitis / classification
  • Osteomyelitis / drug therapy*
  • Osteomyelitis / microbiology*

Substances

  • Anti-Bacterial Agents