Bone marrow fibrosis at diagnosis is associated with TP53 overexpression and adverse prognosis in low-risk myelodysplastic syndrome

Br J Haematol. 2018 May;181(4):547-549. doi: 10.1111/bjh.14656. Epub 2017 Mar 20.
No abstract available

Keywords: TP53; myelodysplastic syndrome; myelofibrosis; prognosis.

Publication types

  • Letter

MeSH terms

  • Aged
  • Disease-Free Survival
  • Female
  • Gene Expression Regulation*
  • Humans
  • Male
  • Middle Aged
  • Myelodysplastic Syndromes* / diagnosis
  • Myelodysplastic Syndromes* / metabolism
  • Myelodysplastic Syndromes* / mortality
  • Primary Myelofibrosis* / diagnosis
  • Primary Myelofibrosis* / metabolism
  • Primary Myelofibrosis* / mortality
  • Survival Rate
  • Tumor Suppressor Protein p53 / biosynthesis*

Substances

  • TP53 protein, human
  • Tumor Suppressor Protein p53