Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference

J Pediatr Gastroenterol Nutr. 2017 Sep;65(3):e53-e59. doi: 10.1097/MPG.0000000000001564.


As pediatric liver transplantation comes of age, experts gathered to discuss current paradigms and define gaps in knowledge warranting research to further improve patient and graft outcomes. Identified areas ripe for collaborative research include understanding the molecular and cellular mechanisms of tolerance and the role of donor-specific antibodies, considering ways to expand donor pool, minimizing long-term side effects of immunosuppression, and fine-tuning surgical techniques to minimize biliary and vascular complications.

Publication types

  • Consensus Development Conference

MeSH terms

  • Child
  • Drug Administration Schedule
  • Graft Rejection / diagnosis
  • Graft Rejection / immunology
  • Graft Rejection / prevention & control
  • Graft Survival
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Liver Transplantation*
  • Outcome Assessment, Health Care
  • Pediatrics
  • Postoperative Complications / diagnosis
  • Postoperative Complications / therapy
  • Quality of Life
  • Tissue and Organ Procurement / methods


  • Immunosuppressive Agents