C3 nephritic factors: A changing landscape

J Allergy Clin Immunol. 2017 Jul;140(1):57-59. doi: 10.1016/j.jaci.2017.02.018. Epub 2017 Mar 16.
No abstract available

Keywords: C3 glomerulopathy; C3 nephritic factor; alternative complement activation; dense-deposit disease; eculizumab; membranoproliferative glomerulonephritis; partial lipodystrophy.

Publication types

  • Editorial

MeSH terms

  • Autoantibodies / immunology*
  • Complement C3 Nephritic Factor / immunology*
  • Complement C3 Nephritic Factor / metabolism
  • Complement Pathway, Alternative / immunology*
  • Disease Susceptibility / immunology*
  • Glomerulonephritis, Membranous / diagnosis
  • Glomerulonephritis, Membranous / etiology
  • Glomerulonephritis, Membranous / metabolism
  • Humans
  • Lipodystrophy, Familial Partial / etiology
  • Lipodystrophy, Familial Partial / metabolism
  • Lipodystrophy, Familial Partial / pathology

Substances

  • Autoantibodies
  • Complement C3 Nephritic Factor