Vitamin D receptor expression and hepcidin levels in the protection or severity of leprosy: a systematic review

Abstract

Leprosy is a chronic infectious disease whose disequilibrium in the host's genetic, immunological and clinical mechanisms leads to distinct manifestations defining the type of immunological response. This review focuses its attention on the influence of the Vitamin D Receptor and hepcidin expressions that can suggest the protection or severity of leprosy.

Keywords: Hepcidin; Leprosy; Polymorphism; Protection; Severity; Vitamin D receptor.