Effect of supervised exercise training during pregnancy on neonatal and maternal outcomes among overweight and obese women. Secondary analyses of the ETIP trial: A randomised controlled trial

PLoS One. 2017 Mar 21;12(3):e0173937. doi: 10.1371/journal.pone.0173937. eCollection 2017.

Abstract

Background: Maternal obesity associates with complications during pregnancy and childbirth. Our aim was to investigate if exercise during pregnancy in overweight/obese women could influence birth weight or other neonatal and maternal outcomes at delivery.

Material and methods: This is a secondary analysis of a randomised controlled trial of exercise training in pregnancy for women with body mass index (BMI) ≥ 28 kg/m2. Ninety-one women (31.3 ± 4.3 years, BMI 34.5 ± 4.2 kg/m2) were allocated 1:1 to supervised exercise during pregnancy or to standard care. The exercise group was offered three weekly training sessions consisting of 35 minutes of moderate intensity walking/running followed by 25 minutes of strength training. Data from 74 women (exercise 38, control 36) were analysed at delivery.

Results: Birth weight was 3719 ± 695 g in the exercise group and 3912 ± 413 g in the control group (CI -460.96, 74.89, p = 0.16). Birth weight > 4000 g was 35% in the exercise group and 52% in the control group (p = 0.16). Mean gestational age at delivery was 39.1 weeks in the exercise group and 39.5 weeks in the control group (CI -1.33, 0.43, p = 0.31). No significant between-group differences were found in neonatal body size, skinfold thickness, placental weight ratio, or Apgar score. The prevalence of caesarean section was 24% in the exercise group and 17% in the control group (CI 0.20, 2.05, p = 0.57). Mean length of hospital stay was 4.8 days in the exercise group and 4.5 days in the control group (CI -0.45, 1.00, p = 0.45).

Conclusions: Offering supervised exercise during pregnancy for overweight and obese women did not influence birth weight or other neonatal and maternal outcomes at delivery. However our trial was limited by low sample size and poor adherence to the exercise protocol, and further research is needed.

Trial registration: ClinicalTrials.gov NCT01243554.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Birth Weight
  • Exercise Therapy / methods*
  • Female
  • Humans
  • Infant, Newborn
  • Obesity / complications*
  • Obesity / therapy*
  • Overweight / complications*
  • Overweight / therapy*
  • Pregnancy
  • Pregnancy Complications / therapy*
  • Pregnancy Outcome

Associated data

  • ClinicalTrials.gov/NCT01243554

Grants and funding

The present trial was supported by grants from The Liaison Committee between the Central Norway Regional Health Authority (RHA) (To author KKG, grant number: 46056728) and the Norwegian University of Science and Technology (NTNU), and The Norwegian Fund for Post-Graduate Training in Physiotherapy (To author SM, grant number: 7-370-00/08A). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.