A new iridoid glycoside and a new cinnamoyl glycoside from Scrophularia ningpoensis Hemsl

Jun Zhang; Fanny C F Ip; Yan Liang; Nancy Y Ip; Ba-Lian Zhong; Chun-Wang Lai; Shi-Hai Xu

doi:10.1080/14786419.2017.1306704

A new iridoid glycoside and a new cinnamoyl glycoside from Scrophularia ningpoensis Hemsl

Nat Prod Res. 2017 Oct;31(20):2361-2368. doi: 10.1080/14786419.2017.1306704. Epub 2017 Mar 22.

Authors

Jun Zhang^{1

2

3}, Fanny C F Ip², Yan Liang^{1

2}, Nancy Y Ip², Ba-Lian Zhong¹, Chun-Wang Lai¹, Shi-Hai Xu³

Affiliations

¹ a National Engineering Research Center of Navel Orange , Gannan Normal University , Ganzhou , P.R. China.
² b Division of Life Science , The Hong Kong University of Science and Technology , Hong Kong , P.R. China.
³ c College of Science and Engineering , Jinan University , Guangzhou , P.R. China.

PMID: 28326841
DOI: 10.1080/14786419.2017.1306704

Abstract

A new iridoid glycoside, namely 8-O-(threo-2, 3-dihydroxyl-3-phenyl-propionoyl)-harpagide (1), along with a new cinnamoyl glycoside named as cis-sibirioside A (2), were isolated from Scrophularia ningpoensis Hemsl. Their chemical structures were completely established by spectroscopic methods and comparison with related literatures. Compound 1 exhibited moderate antifouling effect against the settlement of Balanus amphitrite larvae with IC₅₀ being 13.5 μg/mL and LC₅₀ > 25 μg/mL.

Keywords: Scrophularia ningpoensis Hemsl; antifouling; cinnamoyl glycoside; iridoid glycoside.

MeSH terms

Animals
Biofouling / prevention & control*
China
Iridoid Glycosides / isolation & purification
Iridoid Glycosides / pharmacology*
Molecular Structure
Phytochemicals / isolation & purification
Phytochemicals / pharmacology
Plant Roots / chemistry
Scrophularia / chemistry*
Thoracica / drug effects*

Substances

Iridoid Glycosides
Phytochemicals