Rationale: The great auricular nerve can be damaged by the neck surgery, tumor, and long-time pressure on the neck. But, great auricular neuralgia is very rare condition. It was managed by several medication and landmark-based great auricular nerve block with poor prognosis.
Patient concerns: A 25-year-old man presented with a pain in the left lateral neck and auricle.
Diagnosis: He was diagnosed with great auricular neuralgia.
Interventions: His pain was not reduced by medication. Therefore, the great auricular nerve block with local anesthetics and steroid was performed under ultrasound guidance.
Outcomes: Ultrasound guided great auricular nerve block alleviated great auricular neuralgia.
Lessons: This medication-resistant great auricular neuralgia was treated by the ultrasound guided great auricular nerve block with local anesthetic agent and steroid. Therefore, great auricular nerve block can be a good treatment option of medication resistant great auricular neuralgia.