Black tea supplementation augments redox balance in rats: relevance to aging

Arch Physiol Biochem. 2017 Oct;123(4):212-218. doi: 10.1080/13813455.2017.1302963. Epub 2017 Mar 23.

Abstract

Several health beneficial effects have been attributed to tea consumption, most of the effects are due to the strong antioxidant property of tea catechins. The present study evaluates the effect of black tea extract (BTE) supplementation on the redox balance of rats at different stages in their life span. We have evaluated erythrocyte and plasma redox status in young (4 months), middle-aged (12 months) and old-aged (24 months) male Wistar rats, by quantifying an array of parameters linked to redox status. Our results show that BTE augments redox status, measured in terms of intracellular reduced glutathione (GSH), malondialdehyde (MDA), advanced oxidation protein products (AOPPs), plasma membrane redox system (PMRS) and ferric reducing antioxidant potential (FRAP) of plasma, in rats from three different age groups. This study provides experimental evidence of a strong antioxidant property of black tea on rats in different stages of their lifespan.

Keywords: Free radicals; aging; antioxidants; redox balance.

MeSH terms

  • Advanced Oxidation Protein Products / metabolism
  • Aging / drug effects*
  • Aging / physiology*
  • Animals
  • Antioxidants / pharmacology*
  • Dietary Supplements*
  • Erythrocytes / drug effects
  • Glutathione / metabolism
  • Lipid Peroxidation / drug effects
  • Male
  • Malondialdehyde / metabolism
  • Oxidation-Reduction
  • Oxidative Stress / drug effects*
  • Rats
  • Rats, Wistar
  • Tea / chemistry*

Substances

  • Advanced Oxidation Protein Products
  • Antioxidants
  • Tea
  • Malondialdehyde
  • Glutathione