Treatment of thin endometrium with autologous platelet-rich plasma: a pilot study

JBRA Assist Reprod. 2017 Feb 1;21(1):54-56. doi: 10.5935/1518-0557.20170013.


Endometrium is one of the main factors in pregnancy. During assisted reproductive technology (ART) treatments, some cycles are cancelled due to inadequate endometrial growth. This study was conducted to evaluate the effectiveness of platelet-rich plasma (PRP) in the treatment of thin endometrium. Ten patients with history of inadequate endometrial growth in frozen-thawed embryo transfer (FET) cycles were recruited into the study. Intrauterine infusion of PRP was performed. Endometrial thickness was assessed. Chemical and clinical pregnancies were reported. In all patients, endometrial thickness increased after PRP and embryo transfer was done in all of them. Five patients were pregnant. According to this study, it seems that PRP was effective for endometrial growth in patient with thin endometrium.

Keywords: embryo transfer; frozen-thawed; platelet-rich plasma; thin endometrium.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Embryo Implantation
  • Embryo Transfer
  • Endometrium / pathology*
  • Female
  • Humans
  • Infertility, Female / therapy
  • Pilot Projects
  • Platelet-Rich Plasma*
  • Pregnancy
  • Pregnancy Rate
  • Reproductive Techniques, Assisted*