Case Report: Pediatric Scar Management After Open-heart Surgery

Int J Pharm Compd. 2016 Jul-Aug;20(4):277-280.

Abstract

Tetralogy of Fallot is a congenital disease caused by structural defects within the heart that can lead to cyanosis. The purpose of this case report is to discuss the use of PracaSil-Plus, a proprietary topical anhydrous silicone base containing pracaxi oil, in scar-management therapy, following open-heart surgery on a pediatric patient with tetralogy of Fallot. The Patient and Observer Scar Assessment Scale was the research instrument used to evaluate for efficacy of the scar therapy. Following 8 weeks of treatment with PracaSil-Plus, reduction in scores were observed for scar color, stiffness, thickness, and irregularity, with improvements of 87.5%, 90.0%, 66.7%, and 66.7% from baseline, respectively. The post-treatment scar was similar to normal skin in appearance, with a 77.8% improvement in the total score. These results show that PracaSil-Plus may be a valuable option for practitioners and pharmacists to consider in pediatric scar-management therapy.

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Cardiac Surgical Procedures / adverse effects*
  • Cicatrix / etiology
  • Cicatrix / pathology
  • Cicatrix / therapy*
  • Drug Compounding
  • Fabaceae / chemistry*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Phytotherapy
  • Plant Extracts / administration & dosage*
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Oils / administration & dosage*
  • Plant Oils / chemistry
  • Plant Oils / isolation & purification
  • Plants, Medicinal
  • Silicones / chemistry
  • Tetralogy of Fallot / diagnosis
  • Tetralogy of Fallot / surgery*
  • Time Factors
  • Treatment Outcome
  • Wound Healing / drug effects*

Substances

  • Plant Extracts
  • Plant Oils
  • Silicones