In this issue of Neuron, Newman et al. (2017) image calcium events at single synapses of unanesthetized Drosophila larvae. Synaptic plasticity and homeostatic regulation of synapses is established to be input specific. Furthermore, plasticity forms involve selective recruitment of previously active or silent synapses.
Keywords: Drosophila NMJ; synaptic activation; synaptic depression; synaptic plasticity; synaptic quantal resolution.
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