Management of adult infectious encephalitis in metropolitan France

Med Mal Infect. 2017 May;47(3):206-220. doi: 10.1016/j.medmal.2017.01.006. Epub 2017 Mar 20.


Infectious encephalitis is a severe disease leading to a high mortality and morbidity. The most frequent causes include Herpes simplex virus, Varicella Zoster virus, Listeria monocytogenes, and Mycobacterium tuberculosis. Urgent treatment is required (anti-infective therapy and nonspecific supportive care). The aim of this study was to define treatment strategy, empirical and after microbiological documentation at 48hours, through a systematic literature review.

Keywords: Encéphalite infectieuse; HSV; Infectious encephalitis; Listeria; Tuberculose; Tuberculosis; VZV.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Adult
  • Anti-Infective Agents / therapeutic use
  • Anticonvulsants / therapeutic use
  • Brain Damage, Chronic / prevention & control
  • Critical Care
  • Diagnosis, Differential
  • Disease Management
  • France / epidemiology
  • Hospitalization
  • Humans
  • Hypertonic Solutions / therapeutic use
  • Hypothermia, Induced
  • Infectious Encephalitis / complications
  • Infectious Encephalitis / epidemiology
  • Infectious Encephalitis / therapy*


  • Anti-Infective Agents
  • Anticonvulsants
  • Hypertonic Solutions