Allergenic Ingredients in Facial Wet Wipes

Dermatitis. Nov/Dec 2017;28(6):353-359. doi: 10.1097/DER.0000000000000268.

Abstract

Background: Allergic contact dermatitis commonly occurs on the face. Facial cleansing wipes may be an underrecognized source of allergens.

Objective: The aim of this study was to determine the frequency of potentially allergenic ingredients in facial wet wipes.

Methods: Ingredient lists from name brand and generic facial wipes from 4 large retailers were analyzed.

Results: In the 178 facial wipes examined, a total of 485 ingredients were identified (average, 16.7 ingredients per wipe). Excluding botanicals, the top 15 potentially allergenic ingredients were glycerin (64.0%), fragrance (63.5%), phenoxyethanol (53.9%), citric acid (51.1%), disodium EDTA (44.4%), sorbic acid derivatives (39.3%), tocopherol derivatives (38.8%), polyethylene glycol derivatives (32.6%), glyceryl stearate (31.5%), sodium citrate (29.8%), glucosides (27.5%), cetearyl alcohol (25.8%), propylene glycol (25.3%), sodium benzoate (24.2%), and ceteareth-20 (23.6%)/parabens (23.6%). Of note, methylisothiazolinone (2.2%) and methylchloroisothiazolinone (1.1%) were uncommon. The top potential allergens of botanical origin included Aloe barbadensis (41.0%), chamomile extracts (27.0%), tea extracts (21.3%), Cucumis sativus (20.2%), and Hamamelis virginiana (10.7%).

Conclusions: Many potential allergens are present in facial wet wipes, including fragrances, preservatives, botanicals, glucosides, and propylene glycol.

MeSH terms

  • Allergens / adverse effects
  • Allergens / analysis*
  • Cosmetics / adverse effects
  • Cosmetics / chemistry*
  • Dermatitis, Allergic Contact / etiology*
  • Glucosides / adverse effects
  • Glucosides / analysis
  • Humans
  • Parabens / adverse effects
  • Parabens / analysis
  • Patch Tests
  • Perfume / adverse effects
  • Perfume / analysis
  • Plant Preparations / adverse effects
  • Plant Preparations / analysis
  • Preservatives, Pharmaceutical / adverse effects
  • Preservatives, Pharmaceutical / analysis
  • Propylene Glycol / adverse effects
  • Propylene Glycol / analysis

Substances

  • Allergens
  • Cosmetics
  • Glucosides
  • Parabens
  • Perfume
  • Plant Preparations
  • Preservatives, Pharmaceutical
  • Propylene Glycol