Immunohistochemical localization of beta-nerve growth factor receptors in the forebrain of the rat

D Dawbarn; S J Allen; F M Semenenko

doi:10.1016/0006-8993(88)91175-4

Immunohistochemical localization of beta-nerve growth factor receptors in the forebrain of the rat

Brain Res. 1988 Feb 2;440(1):185-9. doi: 10.1016/0006-8993(88)91175-4.

Authors

D Dawbarn¹, S J Allen, F M Semenenko

Affiliation

¹ Department of Medicine (Care of the Elderly), University of Bristol, Bristol Royal Infirmary, U.K.

PMID: 2833990
DOI: 10.1016/0006-8993(88)91175-4

Abstract

Using a monoclonal antibody (192-IgG) directed against the rat beta-nerve growth factor (beta-NGF) receptor the distribution of beta-NGF receptors in the forebrain of the rat has been determined. beta-NGF receptor-containing cells were located in presumed cholinergic cells of the medial septal nucleus, vertical and horizontal limbs of the diagonal band of Broca and the nucleus basalis of Meynert.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antibodies, Monoclonal
Brain / cytology
Brain / metabolism*
Female
Immunoenzyme Techniques
Nerve Growth Factors / metabolism*
Neurons / cytology
Neurons / metabolism
Rats
Rats, Inbred Strains
Receptors, Cell Surface / immunology
Receptors, Cell Surface / metabolism*
Receptors, Nerve Growth Factor

Substances

Antibodies, Monoclonal
Nerve Growth Factors
Receptors, Cell Surface
Receptors, Nerve Growth Factor