Human T-Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis: The First Case Report in Southeast Asia

AIDS Res Hum Retroviruses. 2017 Jul;33(7):629-631. doi: 10.1089/AID.2016.0275. Epub 2017 May 10.

Abstract

Human T-lymphotropic virus type-1 (HTLV-1) infection was diagnosed in a Thai patient with chronic progressive myelopathy. The phylogenetic tree of the ltr sequencing of HTLV-1 indicated that the virus belongs to the transcontinental genotype of the cosmopolitan subtype A. This is the first case report of HTLV-1-associated myelopathy in Southeast Asia. Awareness of HTLV-1 and related condition should be encouraged in this region and routine screening should be applied to blood donors.

Keywords: Southeast Asia; Thailand; human T-lymphotropic virus-1; paraparesis; spinal cord diseases; tropical spastic.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Genotype*
  • HTLV-I Infections / diagnosis*
  • HTLV-I Infections / pathology*
  • Human T-lymphotropic virus 1 / classification
  • Human T-lymphotropic virus 1 / genetics
  • Human T-lymphotropic virus 1 / isolation & purification*
  • Humans
  • Middle Aged
  • Phylogeny
  • Sequence Analysis, DNA
  • Terminal Repeat Sequences
  • Thailand