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Effects of a Novel Dental Gel on Enamel Surface Recovery From Acid Challenge


Effects of a Novel Dental Gel on Enamel Surface Recovery From Acid Challenge

Tracie Lam et al. Dentistry (Sunnyvale).


Background: Objective was to evaluate the in vivo effects of a novel dental gel (Livionex gelR) vs. a comparison dental gel on the surfaces of pre-eroded enamel chips.

Methods: On days 1-5, after toothbrushing with dentifrice, nine subjects each wore 8 enamel chips mounted on a palatal appliance for 4 h. Enamel blocks were pre-demineralized daily. After 2 day washout, subjects repeated the protocol using fresh chips and the second toothpaste on days 8-12. Samples were evaluated using electron microscopy.

Results: Ten standardized enamel surface photomicrographs/sample (total 1440 images) were evaluated for signs of erosion visually and on a scale of 0-3 by 1 evaluator. No significant differences were found between the 2 groups (p>0.32, 95% C.I.). Minimal surface erosion on approx. 15% of sample area was visible in both groups.

Conclusion: The enamel surface appeared similar after usage of a test or control dentifrice. Based on this study, the test formulation did not affect enamel surface recovery from an erosive challenge.

Practical implications: Dentifrices can contribute to maintaining a healthy enamel surface. An all-natural dental gel formulation with novel anti-plaque mechanism achieved similar recovery from acid challenge to enamel as a control gel.

Keywords: De-mineralization; Dental gel; Dentifrice; Erosion; Re-mineralization; Scanning Electron Microscopy (SEM).


Figure 1
Figure 1
Oral appliance.
Figure 2
Figure 2
Representative SEM photomicrographs (x5000) of specimens after completion of the experimental protocol using the control dental gel. The enamel surface layer is mainly intact. Arrows indicate bacteria on the simple surface.

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    1. Addy M, Shellis RP. Interaction between Attrition, Abrasion and Erosion in Tooth Wear. Monogr Oral Sci. 2006;20:17–31. - PubMed
    1. Lussi A. Erosive Tooth Wear- a Multifactorial Condition of Growing Concern and Increasing Knowledge. Monogr Oral Sci. 2006;20:1–8. - PubMed
    1. Jaeggi T, Lussi A. Prevalence, Incidence and Distribution of Erosion. Monogr Oral Sci. 2006:44–65. - PubMed
    1. Harnack L, Stang J, Story M. Soft Drink Consumption Among US Children and Adolescents: Nutritional Consequences. J Am Diet Assoc. 1999;99:436–441. - PubMed
    1. Gedalia I, Dakuar A, Shapira L, Lewinstein I, Goultschin J, et al. Enamel softening with Coca-Cola and rehardening with milk or saliva. Am J Dent. 1991;4:120–122. - PubMed

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