Case Report: Diabetic Foot Ulcer Infection Treated with Topical Compounded Medications

Int J Pharm Compd. Jan-Feb 2017;21(1):22-27.

Abstract

An adult diabetic male with three toes amputated on his right foot presented with an ulcer infection on his left foot, unresponsive to conventional antifungal oral medication for over two months. The ulcerated foot wound had a large impairment on the patient's quality of life, as determined by the Wound-QoL questionnaire. The compounding pharmacist recommended and the physician prescribed two topical compounded medicines, which were applied twice a day, free of charge at the compounding pharmacy. The foot ulcer infection was completely resolved following 13 days of treatment, with no longer any impairment on the patient's quality of life. This scientific case study highlights the value of pharmaceutical compounding in current therapeutics, the importance of the triad relationship, and the key role of the compounding pharmacist in diabetes care.

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
  • Anti-Inflammatory Agents, Non-Steroidal / chemistry
  • Anti-Inflammatory Agents, Non-Steroidal / economics
  • Antifungal Agents / administration & dosage*
  • Antifungal Agents / adverse effects
  • Antifungal Agents / chemistry
  • Antifungal Agents / economics
  • Clotrimazole / administration & dosage
  • Cost Savings
  • Cost-Benefit Analysis
  • Diabetic Foot / diagnosis
  • Diabetic Foot / drug therapy*
  • Diabetic Foot / economics
  • Diabetic Foot / microbiology
  • Drug Combinations
  • Drug Compounding
  • Drug Costs
  • Humans
  • Ibuprofen / administration & dosage
  • Male
  • Metronidazole / administration & dosage
  • Middle Aged
  • Nifedipine / administration & dosage
  • Pantothenic Acid / administration & dosage
  • Pantothenic Acid / analogs & derivatives
  • Time Factors
  • Treatment Outcome
  • Vasodilator Agents / administration & dosage*
  • Vasodilator Agents / adverse effects
  • Vasodilator Agents / chemistry
  • Vasodilator Agents / economics
  • Vitamin B Complex / administration & dosage*
  • Vitamin B Complex / adverse effects
  • Vitamin B Complex / chemistry
  • Vitamin B Complex / economics
  • Wound Healing / drug effects*
  • Wound Infection / diagnosis
  • Wound Infection / drug therapy*
  • Wound Infection / economics
  • Wound Infection / microbiology

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antifungal Agents
  • Drug Combinations
  • Vasodilator Agents
  • Vitamin B Complex
  • Metronidazole
  • Pantothenic Acid
  • dexpanthenol
  • Clotrimazole
  • Nifedipine
  • Ibuprofen