Phenytoin: a step by step insight into its multiple mechanisms of action-80 years of mechanistic studies in neuropharmacology

J Neurol. 2017 Sep;264(9):2043-2047. doi: 10.1007/s00415-017-8465-4. Epub 2017 Mar 27.
No abstract available

Keywords: Maximal Electroshock Seizure; Radioactive Sodium; Resistant Breast Cancer Cell; Sodium Channel; Sodium Channel Blocker.

Publication types

  • Historical Article

MeSH terms

  • Animals
  • Anticonvulsants / history
  • Anticonvulsants / pharmacology*
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Neuropharmacology / history
  • Phenytoin / history
  • Phenytoin / pharmacology*
  • Voltage-Gated Sodium Channel Blockers / history
  • Voltage-Gated Sodium Channel Blockers / pharmacology*

Substances

  • Anticonvulsants
  • Voltage-Gated Sodium Channel Blockers
  • Phenytoin