A Domino Palladium-Catalyzed Cyclization: One-Pot Synthesis of 4b-Alkyl-10-phenyl-4b,5-dihydroindeno[2,1-a]indenes via Carbopalladation Followed by C-H Activation

Karu Ramesh; Gedu Satyanarayana

doi:10.1021/acs.joc.7b00254

A Domino Palladium-Catalyzed Cyclization: One-Pot Synthesis of 4b-Alkyl-10-phenyl-4b,5-dihydroindeno[2,1-a]indenes via Carbopalladation Followed by C-H Activation

J Org Chem. 2017 Apr 21;82(8):4254-4264. doi: 10.1021/acs.joc.7b00254. Epub 2017 Apr 10.

Authors

Karu Ramesh¹, Gedu Satyanarayana¹

Affiliation

¹ Department of Chemistry, Indian Institute of Technology Hyderabad , Kandi 502 285, Sangareddy, Telangana India.

PMID: 28358198
DOI: 10.1021/acs.joc.7b00254

Abstract

An effective domino one-pot [Pd]-catalysis for the construction of novel tetracyclic compounds was described. This process involved in the construction of three C-C bonds from simple and readily available 1-bromo-2-isopropenylbenzenes and internal alkynes. A variety of fused tetracyclic dihydroindeno-indenes were accomplished.

Publication types

Research Support, Non-U.S. Gov't