Ingestion of oxygenated water enhances lactate clearance kinetics in trained runners

J Int Soc Sports Nutr. 2017 Mar 29:14:9. doi: 10.1186/s12970-017-0166-y. eCollection 2017.


Background: Drinks with higher dissolved oxygen concentrations have in recent times gained popularity as a potential ergogenic aid, despite a lack of evidence regarding their efficacy. The aim of this study was to assess effects of ingestion of an oxygen supplement (OS) on exercise performance and post-exercise recovery in a group of trained runners.

Methods: Trained male runners (n = 25, mean ± SD; age 23 ± 6 years, mass 70 ± 9 kg, BMI 21.9 ± 2.7 kg.m-2 VO2max 64 ±, completed a randomised double blinded, crossover study to assess the effect of ingestion of OS solution on exercise performance and recovery. Trials consisted of a 30min rest period, 5min warm-up, a 5000m treadmill time-trial, and a 30min passive recovery. Participants ingested 6x15mL of either OS or a taste matched placebo during the trials (3 during the rest phase, 1 during exercise and 2 during the recovery). Muscle tissue O2 saturation was measured via near infrared spectroscopy. Blood lactate concentrations were measured prior to, mid-way and directly after the finish of the 5000m time trials and every 3-min during the post-exercise recovery.

Results: Ingestion of OS did not improve exercise performance. No significant differences were observed for muscle tissue O2 saturation at any time-points. However, lactate clearance was significantly improved during recovery in the OS trials. Both AUC (109 ± 32 vs. 123 ± 38 mmol.min, P < 0.05, d = 0.40) and lactate half-life (λ) (1127 ± 272 vs. 1223 ± 334 s, P < 0.05, d = 0.32) were significantly reduced.

Conclusions: Despite no evidence of improved exercise performance, ingestion of OS did enhance post-exercise recovery via increased lactate clearance.

Keywords: Hydration; Recovery; Running.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Cross-Over Studies
  • Double-Blind Method
  • Humans
  • Lactic Acid / blood
  • Lactic Acid / metabolism*
  • Male
  • Muscle, Skeletal / metabolism
  • Oxygen / administration & dosage
  • Oxygen / pharmacology*
  • Physical Endurance / drug effects
  • Running*
  • Sports Nutritional Physiological Phenomena
  • Water / administration & dosage
  • Water / pharmacology*
  • Young Adult


  • Water
  • Lactic Acid
  • Oxygen