(Meth)Acrylate Occupational Contact Dermatitis in Nail Salon Workers: A Case Series

J Cutan Med Surg. 2017 Jul/Aug;21(4):340-344. doi: 10.1177/1203475417701420. Epub 2017 Mar 31.


Background: Recently, many cases of acrylate-associated allergic contact dermatitis have appeared among nail salon workers. Common acrylate-containing products in nail salons include traditional nail polish, ultraviolet-cured shellac nail polish, ultraviolet-cured gel nails, and press-on acrylic nails.

Methods: Nail salon technicians seen in the occupational medicine clinic in 2015 and 2016 were identified, and their patch test results and clinical features were summarized. Patch testing was done with the Chemotechnique (Meth)Acrylate nail series, and either the North American Standard series or the North American Contact Dermatitis Group screening series.

Results: Six patients were identified, all women, ages 38 to 58. Common presentations included erythematous dermatitis of the dorsa of the hands, palms, and forearms and fissures on the fingertips. Less common sites of eruptions included the periorbital region, cheeks, posterior ears, neck, sacral area, lateral thighs, and dorsa of the feet. All patients reacted to hydroxyethyl methacrylate, and 5 patients reacted to ethyl acrylate. Each patient also reacted to (meth)acrylates that are not found on either standard series, including ethyleneglycol dimethacrylate, 2-hydroxypropyl methacrylate, and 2-hydroxyethyl acrylate.

Conclusions: The authors report 6 cases of allergic contact dermatitis to acrylates in nail technicians seen over the past year, representing a new trend in their clinic. These cases are reflective of a growing trend of nail technicians with allergic contact dermatitis associated with occupational (meth)acrylate exposure. Efforts to improve prevention are needed.

Keywords: acrylate; case series; contact dermatitis; dermatitis; dermatology; methacrylate.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cosmetics
  • Dermatitis, Occupational* / diagnosis
  • Dermatitis, Occupational* / pathology
  • Female
  • Fingers / pathology
  • Humans
  • Methacrylates / adverse effects*
  • Middle Aged
  • Occupational Exposure
  • Patch Tests


  • Cosmetics
  • Methacrylates