Severe camphor poisoning, a seven-year observational study

Environ Toxicol Pharmacol. 2017 Jun:52:8-13. doi: 10.1016/j.etap.2017.03.009. Epub 2017 Mar 21.

Abstract

In a retrospective case series from 2007 to 2014, we searched for any accidental/intentional, and recreational cases of pure camphor poisoning through hospital records. Epidemiological data, as well as factors correlated with seizure, were evaluated. Thirty cases including 29 males were recruited with a median age of 18 years (range; 0.2-87). Patient's reported ingestion rate of camphor was 1.5-15 grams. Almost all of the patients (96.7%) were conscious on arrival time and the ingestion to the presentation time ratio was 7±5h. It was observed that in a majority of the cases (53.4%), decreasing libido was the main intent of Camphor ingestion. Nausea and vomiting occurred in 22 (73.3%) cases and tonic-clonic seizure was seen in 12 (40%) patients. Mean presentation time was significantly longer in patients who experienced seizure (9.1±6.1h vs. 5.2±2.8h, p=0.05). No correlation was found between the amount of ingested camphor (grams or mg/kg) and vital signs along with the bio-chemistry results. Not only did all of our cases survive but also they exclusively received supportive care.

Keywords: Convulsion; Drug overdose; Libido; Seizure; Toxicity.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Aphrodisiacs / poisoning*
  • Camphor / poisoning*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Iran / epidemiology
  • Male
  • Middle Aged
  • Young Adult

Substances

  • Aphrodisiacs
  • Camphor