Fertility Preservation for Transgender Adolescents

J Adolesc Health. 2017 Jul;61(1):120-123. doi: 10.1016/j.jadohealth.2017.01.022. Epub 2017 Mar 28.


Purpose: To describe fertility preservation (FP) utilization by transgender adolescents within a pediatric gender clinic between July 2013 and July 2016.

Methods: A retrospective chart review was conducted to abstract demographic and clinical information among adolescents initiating gender-affirming hormones, including patient age at initial FP consultation, birth-assigned sex, race/ethnicity, and outcome of FP consultation.

Results: In our sample of 105 transgender adolescents, a total of 13 (seven transgender men and six transgender women) between the age of 14.2 and 20.6 years were seen in formal consultation for FP before initiating hormones. Of these adolescents, four completed sperm cryopreservation and one completed oocyte cryopreservation.

Conclusions: Rates of FP utilization among transgender youth were low, which is consistent with a recently published report of FP utilization among transgender youth at another pediatric institution. Identified barriers to FP in our sample included cost, invasiveness of procedures, and desire not to delay medical transition.

Keywords: Fertility; Fertility preservation; Gamete cryopreservation; Transgender adolescents; Transgender medicine.

MeSH terms

  • Adolescent
  • Cryopreservation
  • Female
  • Fertility Preservation / statistics & numerical data*
  • Gender Dysphoria / drug therapy
  • Gonadal Steroid Hormones / adverse effects
  • Gonadal Steroid Hormones / therapeutic use
  • Humans
  • Male
  • Oocytes
  • Retrospective Studies
  • Spermatozoa
  • Transgender Persons*
  • Treatment Refusal
  • Young Adult


  • Gonadal Steroid Hormones