Endovascular Therapy for Acute Stroke

Prog Cardiovasc Dis. 2017 May-Jun;59(6):534-541. doi: 10.1016/j.pcad.2017.03.004. Epub 2017 Mar 30.


Stroke is the most common cause of permanent disability, the second most common cause of dementia, and the fourth most common cause of death in the Western world. Recently, based on positive multicenter randomized clinical trials, endovascular therapy for acute stroke has undergone a revolution. Routine mechanical thrombectomy in addition to intravenous thrombolysis has been shown to provide excellent outcomes for patients with proximal anterior circulation occlusions. This procedure reduces disability and benefits are seen across a wide range of age and initial stroke severity. Important features that affect treatment decisions include time of presentation, the patient's clinical status, imaging characteristics, and lab tests. Under optimal conditions, it should be available to patients 24/7, similar to systems offering prompt percutaneous coronary interventions to patients with acute ST-segment elevation myocardial infarctions.

Keywords: Cerebral arterial disease; Endovascular therapy; Stroke.

Publication types

  • Review

MeSH terms

  • Cost-Benefit Analysis
  • Disability Evaluation
  • Endovascular Procedures* / adverse effects
  • Endovascular Procedures* / economics
  • Endovascular Procedures* / methods
  • Health Care Costs
  • Humans
  • Recovery of Function
  • Stroke / diagnosis
  • Stroke / economics
  • Stroke / physiopathology
  • Stroke / therapy*
  • Time Factors
  • Treatment Outcome