A Review on Various Uses of N-Acetyl Cysteine

Cell J. Apr-Jun 2017;19(1):11-17. doi: 10.22074/cellj.2016.4872. Epub 2016 Dec 21.

Abstract

N-acetyl cysteine (NAC), as a nutritional supplement, is a greatly applied antioxidant in vivo and in vitro. NAC is a precursor of L-cysteine that results in glutathione elevation biosynthesis. It acts directly as a scavenger of free radicals, especially oxygen radicals. NAC is a powerful antioxidant. It is also recommended as a potential treatment option for different disorders resulted from generation of free oxygen radicals. Additionally, it is a protected and endured mucolytic drug that mellows tenacious mucous discharges. It has been used for treatment of various diseases in a direct action or in a combination with some other medications. This paper presents a review on various applications of NAC in treatment of several diseases.

Keywords: Antioxidant; N-Acetyl Cysteine; Oxidative Stress.

Publication types

  • Review