Prevalence and Correlates of Probable HIV-Associated Dementia in HIV Outpatients in Ho Chi Minh City, Vietnam

J Int Assoc Provid AIDS Care. 2017 Jul/Aug;16(4):366-375. doi: 10.1177/2325957417701195. Epub 2017 Apr 3.

Abstract

This study identified prevalence and correlates of HIV-associated dementia (HAD) among people living with HIV (PLWHA) in Ho Chi Minh City, Vietnam. Four hundred PLWHA completed a self-report questionnaire and were interviewed by a trained researcher to assess HAD using the International HIV Dementia Scale (IHDS). Clinical information concerning HIV treatment was also extracted from medical records. The results indicate the prevalence of probable HAD based on IHDS score <10.5 was 39.8% (95% confidence interval [CI]: 35.0%-44.5%). Probable HAD was significantly higher among female, older PLWHA and among those with low education level (≤ primary school), moderate level of adherence to HIV medication and HIV stage 3. Those PLWHA with depressive symptoms also had higher odds of having probable HAD (odds ratio = 3.23, 95% CI: 2.05-5.11). These findings underscore the importance of early HAD screening and appropriate referral for further assessment and management of PLWHA especially those with higher risk of HAD.

Keywords: HIV/AIDS; IHDS; Vietnam; dementia; outpatient.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AIDS Dementia Complex / diagnosis
  • AIDS Dementia Complex / drug therapy
  • AIDS Dementia Complex / epidemiology*
  • Adult
  • Age Factors
  • Aged
  • Anti-HIV Agents / therapeutic use
  • Anxiety / epidemiology
  • Depression / epidemiology
  • Educational Status
  • Female
  • Humans
  • Interview, Psychological
  • Male
  • Medication Adherence / statistics & numerical data
  • Middle Aged
  • Prevalence
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Self Report
  • Sex Factors
  • Social Support
  • Vietnam / epidemiology
  • Young Adult

Substances

  • Anti-HIV Agents