Objective: To assess the epidemiology of neonatal Candida blood stream infection.
Methods: Medical records of neonates with Candida blood stream infection over 5 years (September 2010 to August 2015) were reviewed. Clinical details, species distribution and antifungal susceptibility were noted.
Results: 114 neonates developed Candida blood stream infection. Commonly isolated Candida species were C. tropicalis, C. albicans and C. parapsilosis. Susceptibility for fluconazole and amphotericin B was 86.6% and 68.3%, respectively. Central line >7 days and hospital stay >28 days were independent risk factors associated with non-albicans Candida infection.
Conclusion: Early removal of central line, timely fungal culture and antifungal susceptibility are necessary for early and appropriate treatment and better outcome.