The rice LysM receptor-like kinase OsCERK1 is required for the perception of short-chain chitin oligomers in arbuscular mycorrhizal signaling

New Phytol. 2017 Jun;214(4):1440-1446. doi: 10.1111/nph.14539. Epub 2017 Mar 29.

Abstract

The rice lysin-motif (LysM) receptor-like kinase OsCERK1 is now known to have a dual role in both pathogenic and symbiotic interactions. Following the recent discovery that the Oscerk1 mutant is unable to host arbuscular mycorrhizal (AM) fungi, we have examined whether OsCERK1 is directly involved in the perception of the short-chain chitin oligomers (Myc-COs) identified in AM fungal exudates and shown to activate nuclear calcium (Ca2+ ) spiking in the rice root epidermis. An Oscerk1 knockout mutant expressing the cameleon NLS-YC2.60 was used to monitor nuclear Ca2+ signaling following root treatment with either crude fungal exudates or purified Myc-COs. Compared with wild-type rice, Ca2+ spiking responses to AM fungal elicitation were absent in root atrichoblasts of the Oscerk1 mutant. By contrast, rice lines mutated in OsCEBiP, encoding the LysM receptor-like protein which associates with OsCERK1 to perceive chitin elicitors of the host immune defense pathway, responded positively to Myc-COs. These findings provide direct evidence that the bi-functional OsCERK1 plays a central role in perceiving short-chain Myc-CO signals and activating the downstream conserved symbiotic signal transduction pathway.

Keywords: Oryza sativa; LysM receptor-like kinase (RLK); arbuscular mycorrhiza (AM); chitin oligomer signaling; nuclear calcium spiking; plant-microbe interactions; root symbiosis.

MeSH terms

  • Calcium / metabolism
  • Chitin / metabolism*
  • Gene Knockout Techniques
  • Mutation
  • Mycorrhizae / metabolism*
  • Mycorrhizae / physiology
  • Oryza / genetics
  • Oryza / metabolism
  • Oryza / microbiology*
  • Plant Proteins / genetics
  • Plant Proteins / metabolism*
  • Plant Roots / metabolism
  • Plant Roots / microbiology
  • Protein Serine-Threonine Kinases / genetics
  • Protein Serine-Threonine Kinases / metabolism*
  • Signal Transduction

Substances

  • Plant Proteins
  • Chitin
  • Protein Serine-Threonine Kinases
  • Calcium