Mind-body medicine and lifestyle modification in supportive cancer care: A cohort study on a day care clinic program for cancer patients

Psychooncology. 2017 Dec;26(12):2127-2134. doi: 10.1002/pon.4433. Epub 2017 May 9.


Objective: We developed an integrative day care clinic program for cancer patients focusing on mind-body techniques and health-promoting lifestyle modification (7-hour once-per-week group sessions over 12 weeks).

Methods: A cohort study design with a waiting group was implemented. Outcome parameters were assessed at the beginning, at the end of the active program, and at a 6-month follow-up. Patients waiting >4 and <12 weeks before treatment start were allocated to the waiting group and additionally assessed at the start of their day care program. Outcome measures included quality of life (FACT-G, FACT-B/C, WHO-5), fatigue (FACIT-F), depression/anxiety (HADS), and mood states (ASTS). A per protocol analysis using mixed linear models was performed.

Results: One hundred patients were screened on-site for eligibility. Eighty-six cancer survivors (83% female; mean age 53.7 ± 9.7 years; 49% breast cancer) were included into the study. Sixty-two patients were allocated to the intervention group and 24 patients, to the waiting group (mean waiting time 5 ± 1 weeks). Sixty-six data sets were included in the final analysis. Significant improvements were observed in favor of the intervention group after 12 weeks compared with the waiting group at the end of the waiting period for quality of life, anxiety/depression, and fatigue. Results from the 6-month follow-up for the whole study population showed lasting improvement of quality of life.

Conclusions: The program can be considered as an effective means to improve quality of life, fatigue, and mental health of cancer patients. Moreover, it appears to have a sustainable effect, which has to be proved in randomized trials.

Keywords: cancer; day care clinic program; integrative medicine; lifestyle modification; mind-body medicine; mindfulness meditation; naturopathy; oncology.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Affect
  • Aged
  • Ambulatory Care Facilities
  • Behavior Therapy / methods*
  • Breast Neoplasms / psychology
  • Breast Neoplasms / therapy*
  • Cohort Studies
  • Day Care, Medical
  • Depression / therapy
  • Fatigue
  • Female
  • Humans
  • Life Style*
  • Mental Health
  • Middle Aged
  • Mind-Body Therapies / methods*
  • Mindfulness / methods*
  • Prospective Studies
  • Quality of Life / psychology*
  • Treatment Outcome