The Influence of End-of-Life Care on Organ Donor Potential

Am J Transplant. 2017 Jul;17(7):1922-1927. doi: 10.1111/ajt.14286. Epub 2017 May 2.

Abstract

Many patients with acute devastating brain injury die outside intensive care units and could go unrecognized as potential organ donors. We conducted a prospective observational study in seven hospitals in the Netherlands to define the number of unrecognized potential organ donors outside intensive care units, and to identify the effect that end-of-life care has on organ donor potential. Records of all patients who died between January 2013 and March 2014 were reviewed. Patients were included if they died within 72 h after hospital admission outside the intensive care unit due to devastating brain injury, and fulfilled the criteria for organ donation. Physicians of included patients were interviewed using a standardized questionnaire regarding logistics and medical decisions related to end-of-life care. Of the 5170 patients screened, we found 72 additional potential organ donors outside intensive care units. Initiation of end-of-life care in acute settings and lack of knowledge and experience in organ donation practices outside intensive care units can result in under-recognition of potential donors equivalent to 11-34% of the total pool of organ donors. Collaboration with the intensive care unit and adjusting the end-of-life path in these patients is required to increase the likelihood of organ donation.

Keywords: donors and donation: deceased; donors and donation: donor evaluation; health services and outcomes research; organ procurement and allocation; organ transplantation in general.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Death*
  • Female
  • Follow-Up Studies
  • Humans
  • Intensive Care Units*
  • Male
  • Middle Aged
  • Netherlands
  • Prospective Studies
  • Surveys and Questionnaires
  • Terminal Care*
  • Tissue Donors / supply & distribution*
  • Tissue and Organ Procurement / organization & administration*
  • Tissue and Organ Procurement / standards*