Optogenetic activation of dorsal raphe neurons rescues the autistic-like social deficits in Shank3 knockout mice

Cell Res. 2017 Jul;27(7):950-953. doi: 10.1038/cr.2017.52. Epub 2017 Apr 4.

Authors

Junyu Luo¹, Qiru Feng¹, Liping Wei^{2

3}, Minmin Luo^{1

3}

Affiliations

¹ Peking University-Tsinghua University-National Institute of Biological Sciences (PTN) Joint Graduate Program, School of Life Sciences, Tsinghua University, Beijing 100084, China.
² School of Life Sciences, Peking University, Beijing 100871, China.
³ National Institute of Biological Sciences, Beijing 102206, China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Autistic Disorder / pathology*
Dopaminergic Neurons / metabolism
Dorsal Raphe Nucleus / pathology*
Mice, Knockout
Microfilament Proteins
Nerve Tissue Proteins / deficiency*
Nerve Tissue Proteins / metabolism
Neurons / pathology*
Optogenetics / methods*
Social Behavior*

Substances

Microfilament Proteins
Nerve Tissue Proteins
Shank3 protein, mouse