Advancing Keloid Treatment: A Novel Multimodal Approach to Ear Keloids

Dermatol Surg. 2017 Sep;43(9):1164-1169. doi: 10.1097/DSS.0000000000001145.

Abstract

Background/objective: Management of keloids of the pinna, in particular, those located in the helix and antihelix and lobule that occur as complications of ear piercing.

Materials and methods: Retrospective analysis of 49 patients treated with extralesional surgical excision of keloids localized to the ear followed by the application of autologous platelet-rich plasma (PRP) to wound site and postoperative in-office superficial radiation therapy (SRT). Radiation protocol consisted of 1 to 3 fractions, with cumulative dosage ranging from 1,300 to 1,800 cGy. Average follow-up was 24 months to assess for evidence of recurrence and adverse side effects.

Results: Fifty ear keloids were treated with this method, age from 15 to 66 (mean = 32, SD = 16) of which 14 were male and 35 female. Almost 30% (n = 14) of patients acknowledged the source of injury that led to the development of the keloid was ear piercing. Treatment protocol achieved a 94% success rate with 3 patients who reported recurrence.

Conclusion: Surgical excision combined with intraoperative PRP, adjuvant postoperative in-office SRT achieved a 94% nonrecurrence rate on follow-up over a 2-year period. Outcomes provide preliminary, albeit, strong evidence to support this multimodal method as a viable alternative in the management of keloids localized to the ear.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Body Piercing / adverse effects*
  • Combined Modality Therapy
  • Ear Auricle / pathology*
  • Humans
  • Keloid / etiology
  • Keloid / radiotherapy*
  • Keloid / surgery*
  • Middle Aged
  • Plastic Surgery Procedures
  • Platelet-Rich Plasma*
  • Radiotherapy, Adjuvant
  • Recurrence
  • Retrospective Studies
  • Surgical Flaps
  • Young Adult