Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence

Jie Zheng; Yan Luo; Elizabeth Reed; Rebecca Bell; Eric W Brown; Maria Hoffmann

doi:10.1093/gbe/evx065

Whole-Genome Comparative Analysis of Salmonella enterica Serovar Newport Strains Reveals Lineage-Specific Divergence

Genome Biol Evol. 2017 Apr 1;9(4):1047-1050. doi: 10.1093/gbe/evx065.

Authors

Jie Zheng¹, Yan Luo¹, Elizabeth Reed¹, Rebecca Bell¹, Eric W Brown¹, Maria Hoffmann¹

Affiliation

¹ Center for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland.

Abstract

Salmonella enterica subsp. enterica serovar Newport has been associated with various foodborne outbreaks in humans and animals. Phylogenetically, serovar Newport is one of several Salmonella serovars that are polyphyletic. To understand more about the polyphyletic nature of this serovar, six food, environment, and human isolates from different Newport lineages were selected for genome comparison analyses. Whole genome comparisons demonstrated that heterogeneity mostly occurred in the prophage regions. Lineage-specific characteristics were also present in the Salmonella pathogenicity islands and fimbrial operons.

Keywords: Salmonella Newport; complete genome; lineage divergence.

Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution 2017. This work is written by US Government employees and is in the public domain in the US.